Lazio comes into this fixture with strong underlying metrics, particularly defensively, where they have conceded the second-fewest goals in Serie A. Their recent form is positive, with only one loss in their last four league games, including a resilient 1-0 away win against Parma despite receiving two red cards. The primary concern for Maurizio Sarri's side is the absence of suspended attackers Mattia Zaccagni and Toma Basic, as well as defender Mario Gila. This will test their squad depth, but their tactical discipline and home advantage should compensate. Cremonese, meanwhile, have proven they are not relegation fodder, maintaining a mid-table position through a pragmatic approach. However, their form has been patchy (LWWLL in their last five) and they face a significant step up in quality against Lazio. Their head-to-head record is particularly damning; they have lost their last three encounters, conceding 11 goals in the process. From a betting perspective, the odds heavily favor a Lazio win, which is justified. The key analytical question is the margin of victory and the number of goals. While past meetings have been high-scoring, Lazio's more conservative style this season, coupled with their attacking suspensions, suggests a lower-scoring affair. This aligns with the close odds on the Over/Under 2.5 market. Our analysis leads to a confident prediction of a home win, likely secured with a clean sheet. A 2-0 scoreline appears the most probable outcome, balancing Lazio's defensive solidity and offensive capabilities even with key absences.